{"product_id":"wc-0efe51bcb5f34c14-50427","title":"Cleveland Clinic Updates in Primary Immunodeficiency 2026","description":"\u003cdiv\u003e\r\n\u003ch1 data-pm-slice=\"1 1 []\"\u003eCleveland Clinic Updates in Primary Immunodeficiency 2026\u003c\/h1\u003e\r\n\u003ch2\u003eCleveland Clinic Updates in Primary Immunodeficiency 2026 | Inborn Errors of Immunity, CVID, APDS, Antibody Deficiency, Hematologic Complications, Cellular Immune Disorders, Immunoglobulin Replacement, AI \u0026amp; Stem Cell Transplantation\u003c\/h2\u003e\r\nThe \u003cstrong\u003eCleveland Clinic Updates in Primary Immunodeficiency 2026\u003c\/strong\u003e symposium provides a comprehensive, evidence-based educational review of common and rare primary immunodeficiency disorders, also known as \u003cstrong\u003einborn errors of immunity (IEI)\u003c\/strong\u003e.\r\n\r\nOrganized by the \u003cstrong\u003eCleveland Clinic Center for Continuing Education\u003c\/strong\u003e, this two-day educational program brings together nationally recognized experts in clinical immunology, allergy, hematology, rheumatology, infectious diseases, dermatology, and transplantation.\r\n\r\nHeld September 18–19, 2026, at the InterContinental Hotel \u0026amp; Conference Center in Cleveland, Ohio, with in-person and livestream participation options, the symposium examines important advances in the diagnosis, classification, and management of complex immune system disorders.\r\n\r\nInborn errors of immunity represent a group of more than 600 complex, chronic disorders affecting different components of the immune system. Patients may experience recurrent infections, autoimmune complications, hematologic abnormalities, chronic inflammation, immune dysregulation, and increased susceptibility to certain malignancies.\r\n\r\nThe \u003cstrong\u003eCleveland Clinic Primary Immunodeficiency 2026\u003c\/strong\u003e curriculum addresses common variable immunodeficiency (CVID), activated PI3K delta syndrome (APDS), specific antibody deficiency, chronic neutropenia, immune thrombocytopenia, cellular immune defects, idiopathic CD4 lymphocytopenia, chronic granulomatous disease, and complex immunologic conditions.\r\n\r\nThe symposium also examines emerging approaches involving artificial intelligence, immunoglobulin replacement therapy, biologic medications, antimicrobial prophylaxis, and hematopoietic stem cell transplantation.\r\n\r\nThrough expert presentations, multidisciplinary panel discussions, and challenging clinical cases, the program emphasizes earlier recognition of immune dysfunction, accurate diagnosis, individualized treatment strategies, and improved patient outcomes.\r\n\u003ch2\u003eCourse Details\u003c\/h2\u003e\r\n\u003cul data-spread=\"false\"\u003e\r\n \t\u003cli\u003e\n\u003cstrong\u003eCourse:\u003c\/strong\u003e Cleveland Clinic Updates in Primary Immunodeficiency 2026\u003c\/li\u003e\r\n \t\u003cli\u003e\n\u003cstrong\u003eOfficial Event:\u003c\/strong\u003e Updates in Primary Immunodeficiency 2026 CME Symposium\u003c\/li\u003e\r\n \t\u003cli\u003e\n\u003cstrong\u003eProvider:\u003c\/strong\u003e Cleveland Clinic Center for Continuing Education\u003c\/li\u003e\r\n \t\u003cli\u003e\n\u003cstrong\u003eInstitution:\u003c\/strong\u003e Cleveland Clinic\u003c\/li\u003e\r\n \t\u003cli\u003e\n\u003cstrong\u003eDates:\u003c\/strong\u003e September 18–19, 2026\u003c\/li\u003e\r\n \t\u003cli\u003e\n\u003cstrong\u003eLocation:\u003c\/strong\u003e Cleveland, Ohio, USA\u003c\/li\u003e\r\n \t\u003cli\u003e\n\u003cstrong\u003eVenue:\u003c\/strong\u003e InterContinental Hotel \u0026amp; Conference Center\u003c\/li\u003e\r\n \t\u003cli\u003e\n\u003cstrong\u003eVenue Address:\u003c\/strong\u003e 9801 Carnegie Avenue, Cleveland, OH 44106\u003c\/li\u003e\r\n \t\u003cli\u003e\n\u003cstrong\u003eOfficial Conference Format:\u003c\/strong\u003e In-Person and Live Stream\u003c\/li\u003e\r\n \t\u003cli\u003e\n\u003cstrong\u003eDuration:\u003c\/strong\u003e Two Days\u003c\/li\u003e\r\n \t\u003cli\u003e\n\u003cstrong\u003ePrimary Specialty:\u003c\/strong\u003e Allergy \u0026amp; Immunology\u003c\/li\u003e\r\n \t\u003cli\u003e\n\u003cstrong\u003eAdditional Focus:\u003c\/strong\u003e Hematology, Rheumatology, Infectious Diseases, Internal Medicine, Dermatology and Transplantation\u003c\/li\u003e\r\n \t\u003cli\u003e\n\u003cstrong\u003eLanguage:\u003c\/strong\u003e English\u003c\/li\u003e\r\n \t\u003cli\u003e\n\u003cstrong\u003eCourse Director:\u003c\/strong\u003e James Fernandez, MD, PhD\u003c\/li\u003e\r\n \t\u003cli\u003e\n\u003cstrong\u003eEducational Sessions:\u003c\/strong\u003e 6 Major Sessions\u003c\/li\u003e\r\n \t\u003cli\u003e\n\u003cstrong\u003eOfficial AMA CME:\u003c\/strong\u003e Up to 12.50 AMA PRA Category 1 Credits™\u003c\/li\u003e\r\n \t\u003cli\u003e\n\u003cstrong\u003eAAPA CME:\u003c\/strong\u003e Up to 12.50 Category 1 CME Credits\u003c\/li\u003e\r\n \t\u003cli\u003e\n\u003cstrong\u003eANCC Nursing Credit:\u003c\/strong\u003e Up to 12.50 Contact Hours\u003c\/li\u003e\r\n \t\u003cli\u003e\n\u003cstrong\u003eOriginal Participant Materials:\u003c\/strong\u003e Faculty Presentations in PDF Format and Post-Course Recordings\u003c\/li\u003e\r\n\u003c\/ul\u003e\r\nCleveland Clinic confirms that registered in-person and livestream participants receive access to faculty presentation PDFs and post-course recordings, with the recordings designated as non-CME.\r\n\r\nThese benefits apply to eligible participants in the original educational activity and are not automatically included in separately distributed MedicalAmboss educational files.\r\n\u003ch2\u003eTarget Audience\u003c\/h2\u003e\r\nThe symposium is designed for healthcare professionals involved in diagnosing and managing patients with primary immunodeficiency, immune dysregulation, and complex or recurrent infections.\r\n\r\nThe target audience includes:\r\n\u003cul data-spread=\"false\"\u003e\r\n \t\u003cli\u003eClinical Immunologists\u003c\/li\u003e\r\n \t\u003cli\u003eAllergists\u003c\/li\u003e\r\n \t\u003cli\u003eAllergy and Immunology Specialists\u003c\/li\u003e\r\n \t\u003cli\u003eInfectious Disease Physicians\u003c\/li\u003e\r\n \t\u003cli\u003eRheumatologists\u003c\/li\u003e\r\n \t\u003cli\u003eHematologists\u003c\/li\u003e\r\n \t\u003cli\u003eMedical Oncologists\u003c\/li\u003e\r\n \t\u003cli\u003ePediatricians\u003c\/li\u003e\r\n \t\u003cli\u003eInternal Medicine Physicians\u003c\/li\u003e\r\n \t\u003cli\u003ePrimary Care Physicians\u003c\/li\u003e\r\n \t\u003cli\u003eFamily Medicine Physicians\u003c\/li\u003e\r\n \t\u003cli\u003eDermatologists\u003c\/li\u003e\r\n \t\u003cli\u003eTransplant Specialists\u003c\/li\u003e\r\n \t\u003cli\u003eClinical Pathologists\u003c\/li\u003e\r\n \t\u003cli\u003ePhysician Assistants\u003c\/li\u003e\r\n \t\u003cli\u003eNurse Practitioners\u003c\/li\u003e\r\n \t\u003cli\u003eRegistered Nurses\u003c\/li\u003e\r\n \t\u003cli\u003eAdvanced Practice Providers\u003c\/li\u003e\r\n \t\u003cli\u003eMedical Residents\u003c\/li\u003e\r\n \t\u003cli\u003eClinical Fellows\u003c\/li\u003e\r\n \t\u003cli\u003eOther Healthcare Professionals Interested in Immune Disorders\u003c\/li\u003e\r\n\u003c\/ul\u003e\r\nThe program is particularly relevant to clinicians managing patients with recurrent infections, unexplained immune abnormalities, autoimmune complications, hematologic disorders, and suspected inborn errors of immunity.\r\n\u003ch2\u003eProgram Overview\u003c\/h2\u003e\r\nPrimary immunodeficiency disorders represent a diverse group of inherited and acquired immune system abnormalities that can affect antibody production, cellular immunity, immune regulation, and host defense.\r\n\r\nAlthough historically recognized through recurrent infections, inborn errors of immunity may also present with autoimmune disease, chronic inflammation, hematologic complications, malignancy, and other complex clinical manifestations.\r\n\r\nThe \u003cstrong\u003eCleveland Clinic Updates in Primary Immunodeficiency 2026\u003c\/strong\u003e program addresses these clinical challenges through six structured educational sessions.\r\n\r\nThe curriculum covers:\r\n\u003cul data-spread=\"false\"\u003e\r\n \t\u003cli\u003eCommon Variable Immunodeficiency\u003c\/li\u003e\r\n \t\u003cli\u003eCVID-Like Syndromes\u003c\/li\u003e\r\n \t\u003cli\u003eActivated PI3K Delta Syndrome\u003c\/li\u003e\r\n \t\u003cli\u003eSpecific Antibody Deficiency\u003c\/li\u003e\r\n \t\u003cli\u003eDiagnostic Vaccination Guidelines\u003c\/li\u003e\r\n \t\u003cli\u003eImmunoglobulin E Interpretation\u003c\/li\u003e\r\n \t\u003cli\u003eChronic Neutropenia\u003c\/li\u003e\r\n \t\u003cli\u003eImmune Thrombocytopenia\u003c\/li\u003e\r\n \t\u003cli\u003eCancer Risk in Immunodeficiency\u003c\/li\u003e\r\n \t\u003cli\u003eIdiopathic CD4 Lymphocytopenia\u003c\/li\u003e\r\n \t\u003cli\u003eJob's Syndrome\u003c\/li\u003e\r\n \t\u003cli\u003eChronic Mucocutaneous Candidiasis\u003c\/li\u003e\r\n \t\u003cli\u003eMendelian Susceptibility to Mycobacterial Disease\u003c\/li\u003e\r\n \t\u003cli\u003eChronic Granulomatous Disease\u003c\/li\u003e\r\n \t\u003cli\u003eComplex Immunology Diagnostic Evaluation\u003c\/li\u003e\r\n \t\u003cli\u003eArtificial Intelligence in Immunology\u003c\/li\u003e\r\n \t\u003cli\u003eBiologic Therapy in Immunocompromised Patients\u003c\/li\u003e\r\n \t\u003cli\u003eImmunoglobulin Replacement Therapy\u003c\/li\u003e\r\n \t\u003cli\u003eAntibiotic Resistance\u003c\/li\u003e\r\n \t\u003cli\u003eAntimicrobial Prophylaxis\u003c\/li\u003e\r\n \t\u003cli\u003eHematopoietic Stem Cell Transplantation\u003c\/li\u003e\r\n \t\u003cli\u003eMusculoskeletal Pain in Antibody Deficiency\u003c\/li\u003e\r\n \t\u003cli\u003eChronic Sinusitis\u003c\/li\u003e\r\n \t\u003cli\u003eChallenging Clinical Cases\u003c\/li\u003e\r\n \t\u003cli\u003eMultidisciplinary Management\u003c\/li\u003e\r\n\u003c\/ul\u003e\r\nThe course integrates clinical diagnosis, immunologic investigation, treatment advances, and practical case-based decision-making.\r\n\u003ch2\u003eLearning Objectives\u003c\/h2\u003e\r\nAfter completing the original educational activity, participants should be better able to:\r\n\u003col start=\"1\" data-spread=\"true\"\u003e\r\n \t\u003cli\u003eProvide an update on common variable immunodeficiency syndrome and research on IgE levels in immunodeficiency.\u003c\/li\u003e\r\n \t\u003cli\u003eDescribe advances in specific antibody deficiency and utilize vaccine testing guidelines.\u003c\/li\u003e\r\n \t\u003cli\u003eSummarize recent advancements in identifying and treating hematologic complications, including chronic neutropenia and immune thrombocytopenia.\u003c\/li\u003e\r\n \t\u003cli\u003eDiscuss the increased cancer risks in immunocompromised patients and their implications for cancer screening.\u003c\/li\u003e\r\n \t\u003cli\u003eReview the clinical presentation, pathogenesis, diagnosis, and treatment of various immune disorders caused by cellular defects.\u003c\/li\u003e\r\n \t\u003cli\u003eRecognize, assess, and diagnose common symptoms seen in immunocompromised patients to help improve patient outcomes through earlier diagnosis.\u003c\/li\u003e\r\n \t\u003cli\u003eDefine uses of artificial intelligence to improve and individualize therapy in patients with immune dysfunction.\u003c\/li\u003e\r\n \t\u003cli\u003eCritically appraise innovations in immunoglobulin replacement therapy, gene therapy, and stem cell transplantation in the treatment of immunodeficiency syndromes.\u003c\/li\u003e\r\n \t\u003cli\u003eSummarize the efficacy, side effects, and clinical implications of therapeutic options in management strategies for patients with complex immunodeficiency diseases.\u003c\/li\u003e\r\n\u003c\/ol\u003e\r\n\u003cdiv\u003e\r\n\r\n\u003chr\u003e\r\n\r\n\u003c\/div\u003e\r\n\u003ch1\u003eOfficial Program Topics\u003c\/h1\u003e\r\n\u003ch2\u003eDay 1 – Friday, September 18, 2026\u003c\/h2\u003e\r\n\u003cem\u003eAll times are Eastern Time.\u003c\/em\u003e\r\n\u003ch3\u003eWelcome and Introductions\u003c\/h3\u003e\r\n\u003cstrong\u003e7:50 AM\u003c\/strong\u003e\r\n\r\n\u003cstrong\u003eFaculty:\u003c\/strong\u003e James Fernandez, MD, PhD\r\n\r\nThe opening session introduces the educational objectives of the symposium and its focus on contemporary diagnosis and management of primary immunodeficiency disorders.\r\n\u003ch2\u003eSession 1 – Humoral Deficiency\u003c\/h2\u003e\r\n\u003cstrong\u003eModerator:\u003c\/strong\u003e James Fernandez, MD, PhD\r\n\u003ch3\u003eCVID – The Latest\u003c\/h3\u003e\r\n\u003cstrong\u003e8:00 AM\u003c\/strong\u003e\r\n\r\n\u003cstrong\u003eFaculty:\u003c\/strong\u003e Charlotte Cunningham-Rundles, MD, PhD\r\n\r\nThis presentation reviews common variable immunodeficiency, one of the most clinically recognized primary antibody deficiency syndromes.\r\n\r\nImportant considerations include:\r\n\u003cul data-spread=\"false\"\u003e\r\n \t\u003cli\u003eCommon Variable Immunodeficiency\u003c\/li\u003e\r\n \t\u003cli\u003eAntibody Production Defects\u003c\/li\u003e\r\n \t\u003cli\u003eHypogammaglobulinemia\u003c\/li\u003e\r\n \t\u003cli\u003eRecurrent Infections\u003c\/li\u003e\r\n \t\u003cli\u003eImmunoglobulin Assessment\u003c\/li\u003e\r\n \t\u003cli\u003eVaccine Antibody Responses\u003c\/li\u003e\r\n \t\u003cli\u003eImmune Dysregulation\u003c\/li\u003e\r\n \t\u003cli\u003eAutoimmune Manifestations\u003c\/li\u003e\r\n \t\u003cli\u003eNoninfectious Complications\u003c\/li\u003e\r\n \t\u003cli\u003eDiagnostic Evaluation\u003c\/li\u003e\r\n \t\u003cli\u003eTreatment Principles\u003c\/li\u003e\r\n \t\u003cli\u003eLong-Term Monitoring\u003c\/li\u003e\r\n\u003c\/ul\u003e\r\nThe discussion emphasizes developments in CVID research and practical considerations for clinical management.\r\n\u003ch3\u003eCVID Like Syndromes – APDS and Beyond\u003c\/h3\u003e\r\n\u003cstrong\u003e8:30 AM\u003c\/strong\u003e\r\n\r\n\u003cstrong\u003eFaculty:\u003c\/strong\u003e Jocelyn Farmer, MD, PhD\r\n\r\nThis session examines immune disorders that may resemble common variable immunodeficiency.\r\n\r\nA major educational focus is activated PI3K delta syndrome and related conditions.\r\n\r\nImportant concepts include:\r\n\u003cul data-spread=\"false\"\u003e\r\n \t\u003cli\u003eCVID-Like Disorders\u003c\/li\u003e\r\n \t\u003cli\u003eActivated PI3K Delta Syndrome\u003c\/li\u003e\r\n \t\u003cli\u003ePrimary Immune Dysregulation\u003c\/li\u003e\r\n \t\u003cli\u003eRecurrent Infections\u003c\/li\u003e\r\n \t\u003cli\u003eLymphoproliferation\u003c\/li\u003e\r\n \t\u003cli\u003eAbnormal Antibody Responses\u003c\/li\u003e\r\n \t\u003cli\u003eGenetic Immune Disorders\u003c\/li\u003e\r\n \t\u003cli\u003eMolecular Diagnosis\u003c\/li\u003e\r\n \t\u003cli\u003eDifferential Diagnosis\u003c\/li\u003e\r\n \t\u003cli\u003eTargeted Treatment Considerations\u003c\/li\u003e\r\n\u003c\/ul\u003e\r\nThe session supports recognition of complex immune disorders that share clinical features with more common antibody deficiencies.\r\n\u003ch3\u003eUpdates in Specific Antibody Deficiency and Diagnostic Vaccination Guidelines\u003c\/h3\u003e\r\n\u003cstrong\u003e9:00 AM\u003c\/strong\u003e\r\n\r\n\u003cstrong\u003eFaculty:\u003c\/strong\u003e Kelli Williams, MD, MPH\r\n\r\nThis presentation reviews specific antibody deficiency and the clinical use of vaccination responses in immunologic assessment.\r\n\r\nImportant considerations include:\r\n\u003cul data-spread=\"false\"\u003e\r\n \t\u003cli\u003eSpecific Antibody Deficiency\u003c\/li\u003e\r\n \t\u003cli\u003eHumoral Immune Evaluation\u003c\/li\u003e\r\n \t\u003cli\u003eVaccine Response Testing\u003c\/li\u003e\r\n \t\u003cli\u003ePneumococcal Antibody Assessment\u003c\/li\u003e\r\n \t\u003cli\u003eDiagnostic Vaccination Guidelines\u003c\/li\u003e\r\n \t\u003cli\u003eFunctional Antibody Responses\u003c\/li\u003e\r\n \t\u003cli\u003eInterpretation of Laboratory Results\u003c\/li\u003e\r\n \t\u003cli\u003eRecurrent Respiratory Infections\u003c\/li\u003e\r\n \t\u003cli\u003eDiagnostic Decision-Making\u003c\/li\u003e\r\n \t\u003cli\u003eClinical Management\u003c\/li\u003e\r\n\u003c\/ul\u003e\r\nThe discussion emphasizes appropriate interpretation of vaccine responses in patients with suspected immune dysfunction.\r\n\u003ch3\u003eIgE Levels – What Does It Tell Us?\u003c\/h3\u003e\r\n\u003cstrong\u003e9:30 AM\u003c\/strong\u003e\r\n\r\n\u003cstrong\u003eFaculty:\u003c\/strong\u003e Monica Lawrence, MD\r\n\r\nThis session examines the significance of immunoglobulin E levels in the assessment of immune disorders.\r\n\r\nTopics include:\r\n\u003cul data-spread=\"false\"\u003e\r\n \t\u003cli\u003eImmunoglobulin E\u003c\/li\u003e\r\n \t\u003cli\u003eElevated IgE\u003c\/li\u003e\r\n \t\u003cli\u003eLow IgE\u003c\/li\u003e\r\n \t\u003cli\u003eAntibody Deficiency\u003c\/li\u003e\r\n \t\u003cli\u003eAllergic Disease\u003c\/li\u003e\r\n \t\u003cli\u003eImmune Dysregulation\u003c\/li\u003e\r\n \t\u003cli\u003eClinical Interpretation\u003c\/li\u003e\r\n \t\u003cli\u003eLaboratory Evaluation\u003c\/li\u003e\r\n \t\u003cli\u003eDiagnostic Considerations\u003c\/li\u003e\r\n \t\u003cli\u003ePrimary Immunodeficiency\u003c\/li\u003e\r\n\u003c\/ul\u003e\r\nThe presentation reviews how IgE measurements may contribute to broader clinical and laboratory assessment.\r\n\u003ch3\u003eHumoral Deficiency Panel Discussion\u003c\/h3\u003e\r\n\u003cstrong\u003e10:00 AM\u003c\/strong\u003e\r\n\r\n\u003cstrong\u003eFaculty:\u003c\/strong\u003e Course Faculty\r\n\r\nInteractive discussion addressing clinical questions involving antibody deficiency, CVID, APDS, vaccination responses, and IgE interpretation.\r\n\u003ch2\u003eSession 2 – Hematologic Complications\u003c\/h2\u003e\r\n\u003cstrong\u003eModerator:\u003c\/strong\u003e James Fernandez, MD, PhD\r\n\u003ch3\u003eChronic Neutropenia – How to Handle\u003c\/h3\u003e\r\n\u003cstrong\u003e10:40 AM\u003c\/strong\u003e\r\n\r\n\u003cstrong\u003eFaculty:\u003c\/strong\u003e Serhan Unlu, MD\r\n\r\nThis presentation examines chronic neutropenia and its relationship to immune abnormalities.\r\n\r\nRelevant clinical considerations include:\r\n\u003cul data-spread=\"false\"\u003e\r\n \t\u003cli\u003eChronic Neutropenia\u003c\/li\u003e\r\n \t\u003cli\u003eNeutrophil Disorders\u003c\/li\u003e\r\n \t\u003cli\u003eRecurrent Infections\u003c\/li\u003e\r\n \t\u003cli\u003eAutoimmune Neutropenia\u003c\/li\u003e\r\n \t\u003cli\u003eHematologic Evaluation\u003c\/li\u003e\r\n \t\u003cli\u003eDifferential Diagnosis\u003c\/li\u003e\r\n \t\u003cli\u003eLaboratory Investigation\u003c\/li\u003e\r\n \t\u003cli\u003eInfection Risk\u003c\/li\u003e\r\n \t\u003cli\u003eClinical Monitoring\u003c\/li\u003e\r\n \t\u003cli\u003eTreatment Considerations\u003c\/li\u003e\r\n\u003c\/ul\u003e\r\nThe session focuses on a systematic approach to patients with persistent neutropenia.\r\n\u003ch3\u003eITP in Immune Disease\u003c\/h3\u003e\r\n\u003cstrong\u003e11:10 AM\u003c\/strong\u003e\r\n\r\n\u003cstrong\u003eFaculty:\u003c\/strong\u003e Alan Lichtin, MD\r\n\r\nThis session reviews immune thrombocytopenia occurring in association with immune system disorders.\r\n\r\nImportant concepts include:\r\n\u003cul data-spread=\"false\"\u003e\r\n \t\u003cli\u003eImmune Thrombocytopenia\u003c\/li\u003e\r\n \t\u003cli\u003eAutoimmune Cytopenias\u003c\/li\u003e\r\n \t\u003cli\u003ePlatelet Destruction\u003c\/li\u003e\r\n \t\u003cli\u003eBleeding Risk\u003c\/li\u003e\r\n \t\u003cli\u003eImmunodeficiency-Associated Autoimmunity\u003c\/li\u003e\r\n \t\u003cli\u003eDiagnostic Evaluation\u003c\/li\u003e\r\n \t\u003cli\u003eDifferential Diagnosis\u003c\/li\u003e\r\n \t\u003cli\u003eTreatment Considerations\u003c\/li\u003e\r\n \t\u003cli\u003eMonitoring\u003c\/li\u003e\r\n \t\u003cli\u003eMultidisciplinary Management\u003c\/li\u003e\r\n\u003c\/ul\u003e\r\nThe presentation highlights hematologic complications as important manifestations of immune dysregulation.\r\n\u003ch3\u003eCancer in Immunodeficiency – Screening Recommendations\u003c\/h3\u003e\r\n\u003cstrong\u003e11:40 AM\u003c\/strong\u003e\r\n\r\n\u003cstrong\u003eFaculty:\u003c\/strong\u003e John McDonnell, MD, MS\r\n\r\nThis presentation reviews malignancy risk in patients with immunodeficiency syndromes.\r\n\r\nImportant topics include:\r\n\u003cul data-spread=\"false\"\u003e\r\n \t\u003cli\u003eImmunodeficiency and Cancer Risk\u003c\/li\u003e\r\n \t\u003cli\u003eImmune Surveillance\u003c\/li\u003e\r\n \t\u003cli\u003eLymphoproliferative Disorders\u003c\/li\u003e\r\n \t\u003cli\u003eCancer Risk Assessment\u003c\/li\u003e\r\n \t\u003cli\u003eHigh-Risk Populations\u003c\/li\u003e\r\n \t\u003cli\u003eScreening Considerations\u003c\/li\u003e\r\n \t\u003cli\u003eIndividualized Surveillance\u003c\/li\u003e\r\n \t\u003cli\u003eEarly Cancer Detection\u003c\/li\u003e\r\n \t\u003cli\u003eClinical Monitoring\u003c\/li\u003e\r\n \t\u003cli\u003eReferral Pathways\u003c\/li\u003e\r\n\u003c\/ul\u003e\r\nThe discussion examines the implications of impaired immune function for malignancy risk and screening.\r\n\u003ch3\u003eHematologic Complications Panel Discussion\u003c\/h3\u003e\r\n\u003cstrong\u003e12:10 PM\u003c\/strong\u003e\r\n\r\n\u003cstrong\u003eFaculty:\u003c\/strong\u003e Course Faculty\r\n\r\nExpert discussion covering neutropenia, thrombocytopenia, cancer susceptibility, and hematologic abnormalities in patients with immune disorders.\r\n\u003ch2\u003eSession 3 – Cellular Defects\u003c\/h2\u003e\r\n\u003cstrong\u003eModerator:\u003c\/strong\u003e James Fernandez, MD, PhD\r\n\u003ch3\u003eIdiopathic CD4 Lymphocytopenia\u003c\/h3\u003e\r\n\u003cstrong\u003e1:30 PM\u003c\/strong\u003e\r\n\r\n\u003cstrong\u003eFaculty:\u003c\/strong\u003e Jonathan Bernstein, MD\r\n\r\nThis presentation examines idiopathic CD4 lymphocytopenia and the clinical implications of reduced CD4 T-cell counts.\r\n\r\nImportant considerations include:\r\n\u003cul data-spread=\"false\"\u003e\r\n \t\u003cli\u003eCD4 T Lymphocytes\u003c\/li\u003e\r\n \t\u003cli\u003eCellular Immune Deficiency\u003c\/li\u003e\r\n \t\u003cli\u003eIdiopathic CD4 Lymphocytopenia\u003c\/li\u003e\r\n \t\u003cli\u003eOpportunistic Infections\u003c\/li\u003e\r\n \t\u003cli\u003eDiagnostic Evaluation\u003c\/li\u003e\r\n \t\u003cli\u003eDifferential Diagnosis\u003c\/li\u003e\r\n \t\u003cli\u003eImmune Function Testing\u003c\/li\u003e\r\n \t\u003cli\u003eClinical Monitoring\u003c\/li\u003e\r\n \t\u003cli\u003eInfection Prevention\u003c\/li\u003e\r\n \t\u003cli\u003eTreatment Considerations\u003c\/li\u003e\r\n\u003c\/ul\u003e\r\nThe session supports recognition of uncommon cellular immune disorders.\r\n\u003ch3\u003eJob's Syndrome and CMCC – A Dermatologist's View\u003c\/h3\u003e\r\n\u003cstrong\u003e2:00 PM\u003c\/strong\u003e\r\n\r\n\u003cstrong\u003eFaculty:\u003c\/strong\u003e Anthony Fernandez, MD, PhD\r\n\r\nThis presentation explores skin manifestations of selected inborn errors of immunity.\r\n\r\nThe educational focus includes Job's syndrome and chronic mucocutaneous candidiasis.\r\n\r\nTopics include:\r\n\u003cul data-spread=\"false\"\u003e\r\n \t\u003cli\u003eJob's Syndrome\u003c\/li\u003e\r\n \t\u003cli\u003eHyper-IgE Syndromes\u003c\/li\u003e\r\n \t\u003cli\u003eChronic Mucocutaneous Candidiasis\u003c\/li\u003e\r\n \t\u003cli\u003eDermatologic Manifestations\u003c\/li\u003e\r\n \t\u003cli\u003eRecurrent Skin Infections\u003c\/li\u003e\r\n \t\u003cli\u003eImmune Dysregulation\u003c\/li\u003e\r\n \t\u003cli\u003eClinical Recognition\u003c\/li\u003e\r\n \t\u003cli\u003eGenetic Considerations\u003c\/li\u003e\r\n \t\u003cli\u003eDiagnostic Evaluation\u003c\/li\u003e\r\n \t\u003cli\u003eMultidisciplinary Treatment\u003c\/li\u003e\r\n\u003c\/ul\u003e\r\nThe presentation emphasizes dermatologic findings as potential clues to underlying immune dysfunction.\r\n\u003ch3\u003eMendelian Susceptibility to Mycobacterial Disease\u003c\/h3\u003e\r\n\u003cstrong\u003e2:30 PM\u003c\/strong\u003e\r\n\r\n\u003cstrong\u003eFaculty:\u003c\/strong\u003e Vivian Hernandez-Trujillo, MD\r\n\r\nReviews inherited immune defects associated with increased susceptibility to certain mycobacterial infections.\r\n\r\nImportant concepts include:\r\n\u003cul data-spread=\"false\"\u003e\r\n \t\u003cli\u003eMendelian Susceptibility to Mycobacterial Disease\u003c\/li\u003e\r\n \t\u003cli\u003eGenetic Immune Defects\u003c\/li\u003e\r\n \t\u003cli\u003eCellular Immunity\u003c\/li\u003e\r\n \t\u003cli\u003eInterferon-Gamma Pathways\u003c\/li\u003e\r\n \t\u003cli\u003eMycobacterial Infections\u003c\/li\u003e\r\n \t\u003cli\u003eImmune Signaling\u003c\/li\u003e\r\n \t\u003cli\u003eClinical Presentation\u003c\/li\u003e\r\n \t\u003cli\u003eDiagnostic Evaluation\u003c\/li\u003e\r\n \t\u003cli\u003eGenetic Testing\u003c\/li\u003e\r\n \t\u003cli\u003eTreatment Considerations\u003c\/li\u003e\r\n\u003c\/ul\u003e\r\nThe discussion examines how specific defects in immune function may contribute to unusual or recurrent infections.\r\n\u003ch3\u003eChronic Granulomatous Disease in Adults (Including X-Linked)\u003c\/h3\u003e\r\n\u003cstrong\u003e3:00 PM\u003c\/strong\u003e\r\n\r\n\u003cstrong\u003eFaculty:\u003c\/strong\u003e Antoine Azar, MD\r\n\r\nThis session reviews chronic granulomatous disease and its manifestations in adult patients.\r\n\r\nTopics include:\r\n\u003cul data-spread=\"false\"\u003e\r\n \t\u003cli\u003eChronic Granulomatous Disease\u003c\/li\u003e\r\n \t\u003cli\u003eX-Linked CGD\u003c\/li\u003e\r\n \t\u003cli\u003ePhagocyte Dysfunction\u003c\/li\u003e\r\n \t\u003cli\u003eNADPH Oxidase Defects\u003c\/li\u003e\r\n \t\u003cli\u003eRecurrent Bacterial Infections\u003c\/li\u003e\r\n \t\u003cli\u003eFungal Infections\u003c\/li\u003e\r\n \t\u003cli\u003eGranulomatous Inflammation\u003c\/li\u003e\r\n \t\u003cli\u003eDiagnostic Testing\u003c\/li\u003e\r\n \t\u003cli\u003eInfection Prevention\u003c\/li\u003e\r\n \t\u003cli\u003eAntimicrobial Prophylaxis\u003c\/li\u003e\r\n \t\u003cli\u003eLong-Term Management\u003c\/li\u003e\r\n\u003c\/ul\u003e\r\nThe presentation emphasizes recognition of this important phagocytic immune disorder.\r\n\u003ch3\u003eCellular Defects Panel Discussion\u003c\/h3\u003e\r\n\u003cstrong\u003e3:20 PM\u003c\/strong\u003e\r\n\r\n\u003cstrong\u003eFaculty:\u003c\/strong\u003e Course Faculty\r\n\r\nInteractive discussion examining uncommon cellular immune defects and clinical approaches to diagnosis and treatment.\r\n\u003ch2\u003eSession 4 – Complex Disease and Future Options\u003c\/h2\u003e\r\n\u003cstrong\u003eModerator:\u003c\/strong\u003e James Fernandez, MD, PhD\r\n\u003ch3\u003eThinking Outside the Box: Diagnostic Immunology Evaluation of the Complex Immunology Patient\u003c\/h3\u003e\r\n\u003cstrong\u003e4:00 PM\u003c\/strong\u003e\r\n\r\n\u003cstrong\u003eFaculty:\u003c\/strong\u003e Roshini Abraham, PhD, D(ABMLI)\r\n\r\nThis session examines advanced diagnostic approaches to patients with complex or unexplained immunologic abnormalities.\r\n\r\nImportant areas include:\r\n\u003cul data-spread=\"false\"\u003e\r\n \t\u003cli\u003eComplex Immunology Evaluation\u003c\/li\u003e\r\n \t\u003cli\u003eClinical Phenotyping\u003c\/li\u003e\r\n \t\u003cli\u003eImmunoglobulin Testing\u003c\/li\u003e\r\n \t\u003cli\u003eLymphocyte Subset Analysis\u003c\/li\u003e\r\n \t\u003cli\u003eFunctional Immune Testing\u003c\/li\u003e\r\n \t\u003cli\u003eGenetic Testing\u003c\/li\u003e\r\n \t\u003cli\u003eLaboratory Interpretation\u003c\/li\u003e\r\n \t\u003cli\u003eImmune Dysregulation\u003c\/li\u003e\r\n \t\u003cli\u003eDiagnostic Algorithms\u003c\/li\u003e\r\n \t\u003cli\u003eSpecialized Immunology Assessment\u003c\/li\u003e\r\n\u003c\/ul\u003e\r\nThe session emphasizes integrating clinical findings with laboratory investigations.\r\n\u003ch3\u003eUsing Artificial Intelligence to Your Advantage in Practice\u003c\/h3\u003e\r\n\u003cstrong\u003e4:30 PM\u003c\/strong\u003e\r\n\r\n\u003cstrong\u003eFaculty:\u003c\/strong\u003e Nicholas Rider, DO\r\n\r\nThis presentation examines the potential applications of artificial intelligence in immunology practice.\r\n\r\nRelevant considerations include:\r\n\u003cul data-spread=\"false\"\u003e\r\n \t\u003cli\u003eArtificial Intelligence in Immunology\u003c\/li\u003e\r\n \t\u003cli\u003eClinical Decision Support\u003c\/li\u003e\r\n \t\u003cli\u003ePattern Recognition\u003c\/li\u003e\r\n \t\u003cli\u003eDiagnostic Assistance\u003c\/li\u003e\r\n \t\u003cli\u003eMedical Data Analysis\u003c\/li\u003e\r\n \t\u003cli\u003ePersonalized Treatment\u003c\/li\u003e\r\n \t\u003cli\u003eClinical Workflow\u003c\/li\u003e\r\n \t\u003cli\u003eResearch Applications\u003c\/li\u003e\r\n \t\u003cli\u003eLimitations of AI\u003c\/li\u003e\r\n \t\u003cli\u003eHuman Clinical Oversight\u003c\/li\u003e\r\n\u003c\/ul\u003e\r\nThe discussion explores how emerging digital tools may support, rather than replace, clinical expertise.\r\n\u003ch3\u003eBiologics Use in the Immunocompromised\u003c\/h3\u003e\r\n\u003cstrong\u003e5:00 PM\u003c\/strong\u003e\r\n\r\n\u003cstrong\u003eFaculty:\u003c\/strong\u003e Jolan Walter, MD, PhD\r\n\r\nThis session reviews the clinical considerations surrounding biologic therapy in patients with impaired immune function.\r\n\r\nImportant topics include:\r\n\u003cul data-spread=\"false\"\u003e\r\n \t\u003cli\u003eBiologic Medications\u003c\/li\u003e\r\n \t\u003cli\u003eImmune Modulation\u003c\/li\u003e\r\n \t\u003cli\u003eTargeted Therapy\u003c\/li\u003e\r\n \t\u003cli\u003eInfection Risk\u003c\/li\u003e\r\n \t\u003cli\u003eImmunodeficiency\u003c\/li\u003e\r\n \t\u003cli\u003eAutoimmune Complications\u003c\/li\u003e\r\n \t\u003cli\u003eImmune Dysregulation\u003c\/li\u003e\r\n \t\u003cli\u003eTreatment Selection\u003c\/li\u003e\r\n \t\u003cli\u003ePatient Monitoring\u003c\/li\u003e\r\n \t\u003cli\u003eMedication Safety\u003c\/li\u003e\r\n\u003c\/ul\u003e\r\nThe presentation addresses the balance between therapeutic benefits and immune-related risks.\r\n\u003ch3\u003eComplex Disease Panel Discussion\u003c\/h3\u003e\r\n\u003cstrong\u003e5:30 PM\u003c\/strong\u003e\r\n\r\n\u003cstrong\u003eFaculty:\u003c\/strong\u003e Course Faculty\r\n\r\nExpert discussion of diagnostic challenges, artificial intelligence, biologic therapies, and future treatment strategies.\r\n\r\n\u003cstrong\u003e5:45 PM – Day 1 Adjournment\u003c\/strong\u003e\r\n\u003cdiv\u003e\r\n\r\n\u003chr\u003e\r\n\r\n\u003c\/div\u003e\r\n\u003ch2\u003eDay 2 – Saturday, September 19, 2026\u003c\/h2\u003e\r\n\u003ch2\u003eSession 5 – Therapies for IEI \u0026amp; Cases with the Experts\u003c\/h2\u003e\r\n\u003cstrong\u003eModerator:\u003c\/strong\u003e James Fernandez, MD, PhD\r\n\u003ch3\u003eThe Headaches of Immunoglobulin Replacement – Literally and Figuratively\u003c\/h3\u003e\r\n\u003cstrong\u003e8:00 AM\u003c\/strong\u003e\r\n\r\n\u003cstrong\u003eFaculty:\u003c\/strong\u003e James Fernandez, MD, PhD\r\n\r\nThis presentation reviews clinical challenges associated with immunoglobulin replacement therapy.\r\n\r\nImportant considerations include:\r\n\u003cul data-spread=\"false\"\u003e\r\n \t\u003cli\u003eImmunoglobulin Replacement Therapy\u003c\/li\u003e\r\n \t\u003cli\u003eIntravenous Immunoglobulin\u003c\/li\u003e\r\n \t\u003cli\u003eSubcutaneous Immunoglobulin\u003c\/li\u003e\r\n \t\u003cli\u003ePrimary Antibody Deficiency\u003c\/li\u003e\r\n \t\u003cli\u003eTreatment Selection\u003c\/li\u003e\r\n \t\u003cli\u003eDosing Considerations\u003c\/li\u003e\r\n \t\u003cli\u003eAdverse Effects\u003c\/li\u003e\r\n \t\u003cli\u003eInfusion-Related Headaches\u003c\/li\u003e\r\n \t\u003cli\u003eTreatment Tolerability\u003c\/li\u003e\r\n \t\u003cli\u003eLong-Term Monitoring\u003c\/li\u003e\r\n \t\u003cli\u003eIndividualized Therapy\u003c\/li\u003e\r\n\u003c\/ul\u003e\r\nThe session examines practical management issues encountered during immunoglobulin replacement treatment.\r\n\u003ch3\u003eAntibiotic Resistance and Prophylaxis\u003c\/h3\u003e\r\n\u003cstrong\u003e8:30 AM\u003c\/strong\u003e\r\n\r\n\u003cstrong\u003eFaculty:\u003c\/strong\u003e Carlos Isada, MD\r\n\r\nThis presentation reviews infection prevention and antimicrobial management in immunocompromised patients.\r\n\r\nImportant topics include:\r\n\u003cul data-spread=\"false\"\u003e\r\n \t\u003cli\u003eAntimicrobial Resistance\u003c\/li\u003e\r\n \t\u003cli\u003eRecurrent Bacterial Infections\u003c\/li\u003e\r\n \t\u003cli\u003eAntimicrobial Prophylaxis\u003c\/li\u003e\r\n \t\u003cli\u003eInfection Prevention\u003c\/li\u003e\r\n \t\u003cli\u003eAntibiotic Selection\u003c\/li\u003e\r\n \t\u003cli\u003eResistance Patterns\u003c\/li\u003e\r\n \t\u003cli\u003eRisk-Benefit Assessment\u003c\/li\u003e\r\n \t\u003cli\u003eLong-Term Antimicrobial Exposure\u003c\/li\u003e\r\n \t\u003cli\u003eClinical Monitoring\u003c\/li\u003e\r\n \t\u003cli\u003eInfectious Disease Consultation\u003c\/li\u003e\r\n\u003c\/ul\u003e\r\nThe presentation addresses antimicrobial strategies relevant to patients with immune dysfunction.\r\n\u003ch3\u003eHSCT for Adults with Immunodeficiencies\u003c\/h3\u003e\r\n\u003cstrong\u003e9:00 AM\u003c\/strong\u003e\r\n\r\n\u003cstrong\u003eFaculty:\u003c\/strong\u003e Larisa Broglie, MD, MS\r\n\r\nThis session examines hematopoietic stem cell transplantation as a treatment option for selected adults with primary immunodeficiency disorders.\r\n\r\nRelevant areas include:\r\n\u003cul data-spread=\"false\"\u003e\r\n \t\u003cli\u003eHematopoietic Stem Cell Transplantation\u003c\/li\u003e\r\n \t\u003cli\u003eInborn Errors of Immunity\u003c\/li\u003e\r\n \t\u003cli\u003eAdult Transplant Candidates\u003c\/li\u003e\r\n \t\u003cli\u003eTransplant Eligibility\u003c\/li\u003e\r\n \t\u003cli\u003eDonor Selection\u003c\/li\u003e\r\n \t\u003cli\u003eConditioning Regimens\u003c\/li\u003e\r\n \t\u003cli\u003eImmune Reconstitution\u003c\/li\u003e\r\n \t\u003cli\u003eTransplant-Related Complications\u003c\/li\u003e\r\n \t\u003cli\u003eLong-Term Outcomes\u003c\/li\u003e\r\n \t\u003cli\u003eMultidisciplinary Transplant Care\u003c\/li\u003e\r\n\u003c\/ul\u003e\r\nThe discussion explores transplantation as a potentially disease-modifying therapeutic approach in selected immune disorders.\r\n\u003ch3\u003eDifficult Cases with the Experts – Case 1\u003c\/h3\u003e\r\n\u003cstrong\u003e9:30 AM\u003c\/strong\u003e\r\n\r\n\u003cstrong\u003ePresenter:\u003c\/strong\u003e John McDonnell, MD, MS\r\n\r\n\u003cstrong\u003eModerator:\u003c\/strong\u003e James Fernandez, MD, PhD\r\n\r\nA case-based discussion examining complex diagnostic and management challenges in immunodeficiency.\r\n\r\nThe session emphasizes:\r\n\u003cul data-spread=\"false\"\u003e\r\n \t\u003cli\u003eClinical Reasoning\u003c\/li\u003e\r\n \t\u003cli\u003eDifferential Diagnosis\u003c\/li\u003e\r\n \t\u003cli\u003eDiagnostic Testing\u003c\/li\u003e\r\n \t\u003cli\u003eImmune Phenotyping\u003c\/li\u003e\r\n \t\u003cli\u003eTreatment Selection\u003c\/li\u003e\r\n \t\u003cli\u003eExpert Consultation\u003c\/li\u003e\r\n \t\u003cli\u003eMultidisciplinary Management\u003c\/li\u003e\r\n\u003c\/ul\u003e\r\n\u003ch3\u003eDifficult Cases with the Experts – Case 2\u003c\/h3\u003e\r\n\u003cstrong\u003e10:00 AM\u003c\/strong\u003e\r\n\r\n\u003cstrong\u003eFaculty:\u003c\/strong\u003e\r\n\u003cul data-spread=\"false\"\u003e\r\n \t\u003cli\u003eCharlotte Cunningham-Rundles, MD, PhD\u003c\/li\u003e\r\n \t\u003cli\u003eJohn McDonnell, MD, MS\u003c\/li\u003e\r\n \t\u003cli\u003eJolan Walter, MD, PhD\u003c\/li\u003e\r\n\u003c\/ul\u003e\r\nA multidisciplinary case discussion exploring the clinical evaluation and management of complex immunologic conditions.\r\n\r\nThe format provides opportunities to compare diagnostic strategies and therapeutic considerations.\r\n\u003ch2\u003eSession 6 – Common Symptoms in the Immunocompromised\u003c\/h2\u003e\r\n\u003cstrong\u003eModerator:\u003c\/strong\u003e James Fernandez, MD, PhD\r\n\u003ch3\u003eDifficult Cases with the Experts – Case 3\u003c\/h3\u003e\r\n\u003cstrong\u003e10:40 AM\u003c\/strong\u003e\r\n\r\n\u003cstrong\u003eFaculty:\u003c\/strong\u003e Dylan Timberlake, MD\r\n\r\nThis case-based presentation examines challenging clinical situations involving patients with suspected or established immune dysfunction.\r\n\r\nThe session focuses on diagnostic interpretation, clinical reasoning, and individualized management.\r\n\u003ch3\u003eMusculoskeletal Pain in AB Def Patients – Diagnostic and Therapeutic Difficulties\u003c\/h3\u003e\r\n\u003cstrong\u003e11:10 AM\u003c\/strong\u003e\r\n\r\n\u003cstrong\u003eFaculty:\u003c\/strong\u003e Cassandra Calabrese, DO\r\n\r\nThis presentation reviews musculoskeletal symptoms in patients with antibody deficiency.\r\n\r\nImportant considerations include:\r\n\u003cul data-spread=\"false\"\u003e\r\n \t\u003cli\u003eAntibody Deficiency\u003c\/li\u003e\r\n \t\u003cli\u003eMusculoskeletal Pain\u003c\/li\u003e\r\n \t\u003cli\u003eInflammatory Arthritis\u003c\/li\u003e\r\n \t\u003cli\u003eAutoimmune Manifestations\u003c\/li\u003e\r\n \t\u003cli\u003eChronic Inflammation\u003c\/li\u003e\r\n \t\u003cli\u003eDifferential Diagnosis\u003c\/li\u003e\r\n \t\u003cli\u003eRheumatologic Assessment\u003c\/li\u003e\r\n \t\u003cli\u003eImmunologic Evaluation\u003c\/li\u003e\r\n \t\u003cli\u003eTreatment Challenges\u003c\/li\u003e\r\n \t\u003cli\u003eMultidisciplinary Care\u003c\/li\u003e\r\n\u003c\/ul\u003e\r\nThe session highlights the intersection of rheumatology and immunology in patients with complex immune disorders.\r\n\u003ch3\u003eChronic Sinusitis – When to Be Concerned\u003c\/h3\u003e\r\n\u003cstrong\u003e11:40 AM\u003c\/strong\u003e\r\n\r\n\u003cstrong\u003eFaculty:\u003c\/strong\u003e Troy Woodard, MD\r\n\r\nThis session examines chronic sinusitis and its potential relationship to underlying immunodeficiency.\r\n\r\nImportant topics include:\r\n\u003cul data-spread=\"false\"\u003e\r\n \t\u003cli\u003eChronic Rhinosinusitis\u003c\/li\u003e\r\n \t\u003cli\u003eRecurrent Sinus Infections\u003c\/li\u003e\r\n \t\u003cli\u003eAntibody Deficiency\u003c\/li\u003e\r\n \t\u003cli\u003eImmune Dysfunction\u003c\/li\u003e\r\n \t\u003cli\u003eDiagnostic Evaluation\u003c\/li\u003e\r\n \t\u003cli\u003eClinical Warning Signs\u003c\/li\u003e\r\n \t\u003cli\u003eImaging Considerations\u003c\/li\u003e\r\n \t\u003cli\u003eMicrobiological Assessment\u003c\/li\u003e\r\n \t\u003cli\u003eMedical Management\u003c\/li\u003e\r\n \t\u003cli\u003eImmunology Referral\u003c\/li\u003e\r\n \t\u003cli\u003eENT Collaboration\u003c\/li\u003e\r\n\u003c\/ul\u003e\r\nThe presentation focuses on recognizing patients whose recurrent or persistent sinus symptoms may warrant an immunologic investigation.\r\n\u003ch3\u003eCommon Symptoms Panel Discussion\u003c\/h3\u003e\r\n\u003cstrong\u003e12:10 PM\u003c\/strong\u003e\r\n\r\n\u003cstrong\u003eFaculty:\u003c\/strong\u003e Course Faculty\r\n\r\nExpert discussion addressing diagnostic and therapeutic questions related to complex immunodeficiency cases, musculoskeletal symptoms, and chronic sinusitis.\r\n\u003ch3\u003eClosing Remarks\u003c\/h3\u003e\r\n\u003cstrong\u003e12:30 PM\u003c\/strong\u003e\r\n\r\n\u003cstrong\u003eFaculty:\u003c\/strong\u003e James Fernandez, MD, PhD\r\n\r\n\u003cstrong\u003e12:35 PM – Conference Adjournment\u003c\/strong\u003e\r\n\u003cdiv\u003e\r\n\r\n\u003chr\u003e\r\n\r\n\u003c\/div\u003e\r\n\u003ch2\u003eMajor Topics Covered\u003c\/h2\u003e\r\n\u003cul data-spread=\"false\"\u003e\r\n \t\u003cli\u003eCleveland Clinic Updates in Primary Immunodeficiency 2026\u003c\/li\u003e\r\n \t\u003cli\u003ePrimary Immunodeficiency\u003c\/li\u003e\r\n \t\u003cli\u003eInborn Errors of Immunity\u003c\/li\u003e\r\n \t\u003cli\u003eClinical Immunology\u003c\/li\u003e\r\n \t\u003cli\u003eAllergy and Immunology\u003c\/li\u003e\r\n \t\u003cli\u003eCommon Variable Immunodeficiency\u003c\/li\u003e\r\n \t\u003cli\u003eCVID-Like Syndromes\u003c\/li\u003e\r\n \t\u003cli\u003eActivated PI3K Delta Syndrome\u003c\/li\u003e\r\n \t\u003cli\u003eSpecific Antibody Deficiency\u003c\/li\u003e\r\n \t\u003cli\u003eDiagnostic Vaccination Guidelines\u003c\/li\u003e\r\n \t\u003cli\u003eImmunoglobulin E\u003c\/li\u003e\r\n \t\u003cli\u003eImmunoglobulin Testing\u003c\/li\u003e\r\n \t\u003cli\u003eHypogammaglobulinemia\u003c\/li\u003e\r\n \t\u003cli\u003eChronic Neutropenia\u003c\/li\u003e\r\n \t\u003cli\u003eImmune Thrombocytopenia\u003c\/li\u003e\r\n \t\u003cli\u003eAutoimmune Cytopenias\u003c\/li\u003e\r\n \t\u003cli\u003eMalignancy Risk in Immunodeficiency\u003c\/li\u003e\r\n \t\u003cli\u003eIdiopathic CD4 Lymphocytopenia\u003c\/li\u003e\r\n \t\u003cli\u003eJob's Syndrome\u003c\/li\u003e\r\n \t\u003cli\u003eHyper-IgE Syndrome\u003c\/li\u003e\r\n \t\u003cli\u003eChronic Mucocutaneous Candidiasis\u003c\/li\u003e\r\n \t\u003cli\u003eMendelian Susceptibility to Mycobacterial Disease\u003c\/li\u003e\r\n \t\u003cli\u003eChronic Granulomatous Disease\u003c\/li\u003e\r\n \t\u003cli\u003eCellular Immune Defects\u003c\/li\u003e\r\n \t\u003cli\u003ePhagocytic Immune Disorders\u003c\/li\u003e\r\n \t\u003cli\u003eImmunology Diagnostic Testing\u003c\/li\u003e\r\n \t\u003cli\u003eImmune Phenotyping\u003c\/li\u003e\r\n \t\u003cli\u003eArtificial Intelligence in Immunology\u003c\/li\u003e\r\n \t\u003cli\u003eBiologic Therapy\u003c\/li\u003e\r\n \t\u003cli\u003eImmunoglobulin Replacement\u003c\/li\u003e\r\n \t\u003cli\u003eIntravenous Immunoglobulin\u003c\/li\u003e\r\n \t\u003cli\u003eSubcutaneous Immunoglobulin\u003c\/li\u003e\r\n \t\u003cli\u003eAntimicrobial Resistance\u003c\/li\u003e\r\n \t\u003cli\u003eAntibiotic Prophylaxis\u003c\/li\u003e\r\n \t\u003cli\u003eHematopoietic Stem Cell Transplantation\u003c\/li\u003e\r\n \t\u003cli\u003eImmune Reconstitution\u003c\/li\u003e\r\n \t\u003cli\u003eMusculoskeletal Pain\u003c\/li\u003e\r\n \t\u003cli\u003eAutoimmune Complications\u003c\/li\u003e\r\n \t\u003cli\u003eChronic Sinusitis\u003c\/li\u003e\r\n \t\u003cli\u003eRecurrent Infections\u003c\/li\u003e\r\n \t\u003cli\u003eDiagnostic Immunology\u003c\/li\u003e\r\n \t\u003cli\u003eClinical Case Discussions\u003c\/li\u003e\r\n \t\u003cli\u003ePersonalized Immune Therapy\u003c\/li\u003e\r\n \t\u003cli\u003eMultidisciplinary Immunodeficiency Care\u003c\/li\u003e\r\n\u003c\/ul\u003e\r\n\u003ch2\u003eHumoral Immunodeficiency and Antibody Disorders\u003c\/h2\u003e\r\nHumoral immunodeficiencies involve abnormalities affecting antibody production, function, or immune regulation.\r\n\r\nPatients may present with recurrent respiratory infections, abnormal vaccine responses, or systemic complications.\r\n\r\nThe curriculum examines several important disorders and diagnostic concepts:\r\n\u003cul data-spread=\"false\"\u003e\r\n \t\u003cli\u003eCommon Variable Immunodeficiency\u003c\/li\u003e\r\n \t\u003cli\u003eCVID-Like Syndromes\u003c\/li\u003e\r\n \t\u003cli\u003eActivated PI3K Delta Syndrome\u003c\/li\u003e\r\n \t\u003cli\u003eSpecific Antibody Deficiency\u003c\/li\u003e\r\n \t\u003cli\u003eIgE Interpretation\u003c\/li\u003e\r\n \t\u003cli\u003eDiagnostic Vaccine Testing\u003c\/li\u003e\r\n\u003c\/ul\u003e\r\nThe educational program emphasizes integrating clinical history, immunoglobulin measurements, functional antibody assessment, and specialized immunologic investigations.\r\n\u003ch2\u003eHematologic Complications of Immunodeficiency\u003c\/h2\u003e\r\nPatients with primary immunodeficiency may develop hematologic complications beyond recurrent infections.\r\n\r\nThese complications may include immune thrombocytopenia, chronic neutropenia, autoimmune cytopenias, and increased susceptibility to certain malignancies.\r\n\r\nThe symposium reviews:\r\n\u003cul data-spread=\"false\"\u003e\r\n \t\u003cli\u003eNeutropenia Assessment\u003c\/li\u003e\r\n \t\u003cli\u003eImmune Thrombocytopenia\u003c\/li\u003e\r\n \t\u003cli\u003eHematologic Autoimmunity\u003c\/li\u003e\r\n \t\u003cli\u003eCancer Risk\u003c\/li\u003e\r\n \t\u003cli\u003eDiagnostic Evaluation\u003c\/li\u003e\r\n \t\u003cli\u003eScreening Considerations\u003c\/li\u003e\r\n \t\u003cli\u003eManagement Strategies\u003c\/li\u003e\r\n\u003c\/ul\u003e\r\nThe sessions highlight the importance of collaboration between immunologists, hematologists, and other specialists.\r\n\u003ch2\u003eCellular Immune Defects and Rare Immunodeficiency Syndromes\u003c\/h2\u003e\r\nCellular immune disorders may impair host defense against selected infectious organisms or lead to unusual inflammatory and immune manifestations.\r\n\r\nThe program includes presentations covering:\r\n\u003cul data-spread=\"false\"\u003e\r\n \t\u003cli\u003eIdiopathic CD4 Lymphocytopenia\u003c\/li\u003e\r\n \t\u003cli\u003eJob's Syndrome\u003c\/li\u003e\r\n \t\u003cli\u003eChronic Mucocutaneous Candidiasis\u003c\/li\u003e\r\n \t\u003cli\u003eMendelian Susceptibility to Mycobacterial Disease\u003c\/li\u003e\r\n \t\u003cli\u003eChronic Granulomatous Disease\u003c\/li\u003e\r\n\u003c\/ul\u003e\r\nThese disorders illustrate the clinical diversity of inborn errors of immunity and the importance of appropriate immune evaluation.\r\n\u003ch2\u003eImmunoglobulin Replacement Therapy\u003c\/h2\u003e\r\nImmunoglobulin replacement is an important therapeutic approach for selected patients with clinically significant antibody deficiencies.\r\n\r\nThe symposium includes a dedicated discussion of treatment-related challenges.\r\n\r\nRelevant considerations include:\r\n\u003cul data-spread=\"false\"\u003e\r\n \t\u003cli\u003eIntravenous Immunoglobulin\u003c\/li\u003e\r\n \t\u003cli\u003eSubcutaneous Immunoglobulin\u003c\/li\u003e\r\n \t\u003cli\u003eTreatment Indications\u003c\/li\u003e\r\n \t\u003cli\u003eAdministration Approaches\u003c\/li\u003e\r\n \t\u003cli\u003eAdverse Reactions\u003c\/li\u003e\r\n \t\u003cli\u003eTreatment-Associated Headaches\u003c\/li\u003e\r\n \t\u003cli\u003eLong-Term Monitoring\u003c\/li\u003e\r\n \t\u003cli\u003eIndividualized Treatment Planning\u003c\/li\u003e\r\n\u003c\/ul\u003e\r\nThe educational emphasis supports informed selection and ongoing evaluation of replacement therapy.\r\n\u003ch2\u003eArtificial Intelligence and Advanced Immunology Diagnostics\u003c\/h2\u003e\r\nArtificial intelligence and advanced laboratory investigations are becoming increasingly relevant to the assessment of complex immunologic conditions.\r\n\r\nPotential clinical applications include:\r\n\u003cul data-spread=\"false\"\u003e\r\n \t\u003cli\u003eRecognition of Disease Patterns\u003c\/li\u003e\r\n \t\u003cli\u003eInterpretation of Complex Laboratory Results\u003c\/li\u003e\r\n \t\u003cli\u003eClinical Decision Support\u003c\/li\u003e\r\n \t\u003cli\u003eRisk Stratification\u003c\/li\u003e\r\n \t\u003cli\u003eDiagnostic Assistance\u003c\/li\u003e\r\n \t\u003cli\u003ePersonalized Treatment Considerations\u003c\/li\u003e\r\n \t\u003cli\u003eResearch and Data Analysis\u003c\/li\u003e\r\n\u003c\/ul\u003e\r\nThe program includes sessions exploring the potential benefits, limitations, and responsible clinical application of emerging diagnostic technologies.\r\n\u003ch2\u003eStem Cell Transplantation and Advanced Therapy\u003c\/h2\u003e\r\nFor selected patients with serious inborn errors of immunity, hematopoietic stem cell transplantation may offer an important treatment option.\r\n\r\nThe symposium examines transplantation in adults with immunodeficiency disorders.\r\n\r\nImportant considerations include:\r\n\u003cul data-spread=\"false\"\u003e\r\n \t\u003cli\u003ePatient Selection\u003c\/li\u003e\r\n \t\u003cli\u003eTransplant Eligibility\u003c\/li\u003e\r\n \t\u003cli\u003eDonor Compatibility\u003c\/li\u003e\r\n \t\u003cli\u003eImmune Reconstitution\u003c\/li\u003e\r\n \t\u003cli\u003eTreatment-Related Complications\u003c\/li\u003e\r\n \t\u003cli\u003ePost-Transplant Monitoring\u003c\/li\u003e\r\n \t\u003cli\u003eLong-Term Outcomes\u003c\/li\u003e\r\n\u003c\/ul\u003e\r\nThe wider educational objectives also address innovations in gene therapy and other emerging interventions for immunodeficiency syndromes.\r\n\u003ch2\u003eRecurrent Infections and Clinical Warning Signs\u003c\/h2\u003e\r\nRecurrent or unusually severe infections may suggest an underlying immune abnormality.\r\n\r\nClinical presentations requiring careful assessment may include:\r\n\u003cul data-spread=\"false\"\u003e\r\n \t\u003cli\u003eRecurrent Sinusitis\u003c\/li\u003e\r\n \t\u003cli\u003eRecurrent Respiratory Infections\u003c\/li\u003e\r\n \t\u003cli\u003ePersistent or Unusual Infections\u003c\/li\u003e\r\n \t\u003cli\u003eMycobacterial Infections\u003c\/li\u003e\r\n \t\u003cli\u003eFungal Infections\u003c\/li\u003e\r\n \t\u003cli\u003eChronic Neutropenia\u003c\/li\u003e\r\n \t\u003cli\u003eUnexplained Immune Abnormalities\u003c\/li\u003e\r\n \t\u003cli\u003eAssociated Autoimmune Symptoms\u003c\/li\u003e\r\n\u003c\/ul\u003e\r\nThe course emphasizes early recognition, appropriate investigation, and coordinated specialist referral.\r\n\u003ch2\u003eEvidence-Based and Multidisciplinary Immune Care\u003c\/h2\u003e\r\nEffective care for patients with primary immunodeficiency often requires collaboration across several specialties.\r\n\r\nHealthcare teams may include:\r\n\u003cul data-spread=\"false\"\u003e\r\n \t\u003cli\u003eImmunologists\u003c\/li\u003e\r\n \t\u003cli\u003eAllergists\u003c\/li\u003e\r\n \t\u003cli\u003eInfectious Disease Specialists\u003c\/li\u003e\r\n \t\u003cli\u003eHematologists\u003c\/li\u003e\r\n \t\u003cli\u003eRheumatologists\u003c\/li\u003e\r\n \t\u003cli\u003eDermatologists\u003c\/li\u003e\r\n \t\u003cli\u003eTransplant Physicians\u003c\/li\u003e\r\n \t\u003cli\u003eENT Specialists\u003c\/li\u003e\r\n \t\u003cli\u003ePrimary Care Clinicians\u003c\/li\u003e\r\n\u003c\/ul\u003e\r\nThe program emphasizes integrating diagnostic evidence, clinical presentation, immune function testing, treatment options, and patient-specific risks into management decisions.\r\n\u003ch2\u003eCourse Leadership\u003c\/h2\u003e\r\n\u003ch3\u003eJames Fernandez, MD, PhD\u003c\/h3\u003e\r\n\u003cstrong\u003eCourse Director\u003c\/strong\u003e\r\n\u003cul data-spread=\"false\"\u003e\r\n \t\u003cli\u003eVice Chair of Research, Allergy \u0026amp; Immunology\u003c\/li\u003e\r\n \t\u003cli\u003eDepartment of Allergy \u0026amp; Clinical Immunology\u003c\/li\u003e\r\n \t\u003cli\u003eMedical Specialty Institute\u003c\/li\u003e\r\n \t\u003cli\u003eCleveland Clinic\u003c\/li\u003e\r\n\u003c\/ul\u003e\r\nDr. Fernandez serves as the official course director and moderates the six principal educational sessions.\r\n\u003ch2\u003eOfficial Faculty\u003c\/h2\u003e\r\nThe published faculty includes experts from Cleveland Clinic and other major academic medical institutions.\r\n\r\n\u003cstrong\u003eGuest Faculty\u003c\/strong\u003e\r\n\u003cul data-spread=\"false\"\u003e\r\n \t\u003cli\u003eRoshini Abraham, PhD, D(ABMLI)\u003c\/li\u003e\r\n \t\u003cli\u003eAntoine Azar, MD\u003c\/li\u003e\r\n \t\u003cli\u003eJonathan Bernstein, MD\u003c\/li\u003e\r\n \t\u003cli\u003eLarisa Broglie, MD, MS\u003c\/li\u003e\r\n \t\u003cli\u003eCharlotte Cunningham-Rundles, MD, PhD\u003c\/li\u003e\r\n \t\u003cli\u003eJocelyn Farmer, MD, PhD\u003c\/li\u003e\r\n \t\u003cli\u003eVivian Hernandez-Trujillo, MD\u003c\/li\u003e\r\n \t\u003cli\u003eMonica Lawrence, MD\u003c\/li\u003e\r\n \t\u003cli\u003eNicholas Rider, DO\u003c\/li\u003e\r\n \t\u003cli\u003eJolan Walter, MD, PhD\u003c\/li\u003e\r\n \t\u003cli\u003eKelli Williams, MD, MPH\u003c\/li\u003e\r\n \t\u003cli\u003eTroy Woodard, MD\u003c\/li\u003e\r\n\u003c\/ul\u003e\r\n\u003cstrong\u003eCleveland Clinic Faculty\u003c\/strong\u003e\r\n\u003cul data-spread=\"false\"\u003e\r\n \t\u003cli\u003eCassandra Calabrese, DO\u003c\/li\u003e\r\n \t\u003cli\u003eAnthony Fernandez, MD, PhD\u003c\/li\u003e\r\n \t\u003cli\u003eCarlos Isada, MD\u003c\/li\u003e\r\n \t\u003cli\u003eAlan Lichtin, MD\u003c\/li\u003e\r\n \t\u003cli\u003eJohn McDonnell, MD, MS\u003c\/li\u003e\r\n \t\u003cli\u003eDylan Timberlake, MD\u003c\/li\u003e\r\n \t\u003cli\u003eSerhan Unlu, MD\u003c\/li\u003e\r\n\u003c\/ul\u003e\r\nThe faculty bring expertise in antibody deficiencies, complex immune disorders, hematologic complications, recurrent infections, clinical immunology, dermatology, and advanced therapeutic strategies.\r\n\u003ch2\u003eContinuing Medical Education\u003c\/h2\u003e\r\nCleveland Clinic Center for Continuing Education designated the original live activity for a maximum of:\r\n\u003cul data-spread=\"false\"\u003e\r\n \t\u003cli\u003e\u003cstrong\u003e12.50 AMA PRA Category 1 Credits™\u003c\/strong\u003e\u003c\/li\u003e\r\n \t\u003cli\u003e\u003cstrong\u003e12.50 AAPA Category 1 CME Credits\u003c\/strong\u003e\u003c\/li\u003e\r\n \t\u003cli\u003e\u003cstrong\u003e12.50 ANCC Contact Hours\u003c\/strong\u003e\u003c\/li\u003e\r\n\u003c\/ul\u003e\r\nThe course also qualified as an American Board of Allergy \u0026amp; Immunology Lifelong Learning CME Activity for relevant continuing certification requirements.\r\n\r\nCleveland Clinic Center for Continuing Education is jointly accredited by ACCME, ACPE, and ANCC to provide continuing education for healthcare professionals.\r\n\u003ch3\u003eImportant CME Notice\u003c\/h3\u003e\r\nThe credits described above apply to eligible participants in the original Cleveland Clinic educational activity.\r\n\r\nCleveland Clinic states that recordings supplied to official participants after the course are non-CME recordings.\r\n\r\nPurchasing separately distributed educational files through MedicalAmboss does not provide:\r\n\u003cul data-spread=\"false\"\u003e\r\n \t\u003cli\u003eOfficial Cleveland Clinic CME Credits\u003c\/li\u003e\r\n \t\u003cli\u003eContinuing Certification Credits\u003c\/li\u003e\r\n \t\u003cli\u003eOfficial Certificates\u003c\/li\u003e\r\n \t\u003cli\u003eCleveland Clinic Course Registration\u003c\/li\u003e\r\n \t\u003cli\u003eLive Attendance\u003c\/li\u003e\r\n \t\u003cli\u003ePublisher Livestream Access\u003c\/li\u003e\r\n \t\u003cli\u003eOfficial Cleveland Clinic Account Access\u003c\/li\u003e\r\n \t\u003cli\u003ePublisher-Hosted Educational Extras\u003c\/li\u003e\r\n\u003c\/ul\u003e\r\n\u003ch2\u003eWhy This Course Is Relevant\u003c\/h2\u003e\r\nThe \u003cstrong\u003eCleveland Clinic Updates in Primary Immunodeficiency 2026\u003c\/strong\u003e symposium addresses an important and rapidly developing area of clinical medicine.\r\n\r\nInborn errors of immunity include hundreds of disorders with diverse clinical presentations and potentially serious complications.\r\n\r\nHealthcare professionals may encounter patients with:\r\n\u003cul data-spread=\"false\"\u003e\r\n \t\u003cli\u003eRecurrent Infections\u003c\/li\u003e\r\n \t\u003cli\u003eChronic Sinusitis\u003c\/li\u003e\r\n \t\u003cli\u003eAbnormal Vaccine Responses\u003c\/li\u003e\r\n \t\u003cli\u003eAntibody Deficiencies\u003c\/li\u003e\r\n \t\u003cli\u003eCellular Immune Defects\u003c\/li\u003e\r\n \t\u003cli\u003eChronic Neutropenia\u003c\/li\u003e\r\n \t\u003cli\u003eImmune Thrombocytopenia\u003c\/li\u003e\r\n \t\u003cli\u003eAutoimmune Manifestations\u003c\/li\u003e\r\n \t\u003cli\u003eIncreased Cancer Risk\u003c\/li\u003e\r\n \t\u003cli\u003eComplex Diagnostic Findings\u003c\/li\u003e\r\n\u003c\/ul\u003e\r\nThe educational program brings together practical diagnostic strategies, specialized immune disorders, treatment advances, and complex clinical cases.\r\n\r\nIts multidisciplinary focus is relevant to immunologists, allergists, infectious disease specialists, hematologists, rheumatologists, pediatricians, internists, and other healthcare professionals involved in the care of immunocompromised patients.\r\n\u003ch2\u003eOfficial Program Reference and MedicalAmboss Purchase Scope\u003c\/h2\u003e\r\n\u003cstrong\u003eOfficial Cleveland Clinic Course:\u003c\/strong\u003e\r\n\r\n\u003ca href=\"https:\/\/clevelandclinicmeded.com\/live\/courses\/immunodeficiency\/\" data-rich-text-autolink=\"\"\u003ehttps:\/\/clevelandclinicmeded.com\/live\/courses\/immunodeficiency\/\u003c\/a\u003e\r\n\r\n\u003cstrong\u003eOfficial 2026 Agenda:\u003c\/strong\u003e\r\n\r\n\u003ca href=\"https:\/\/clevelandclinicmeded.com\/live\/courses\/immunodeficiency\/agenda.asp\" data-rich-text-autolink=\"\"\u003ehttps:\/\/clevelandclinicmeded.com\/live\/courses\/immunodeficiency\/agenda.asp\u003c\/a\u003e\r\n\r\n\u003cstrong\u003eOfficial Faculty:\u003c\/strong\u003e\r\n\r\n\u003ca href=\"https:\/\/clevelandclinicmeded.com\/live\/courses\/immunodeficiency\/faculty.asp\" data-rich-text-autolink=\"\"\u003ehttps:\/\/clevelandclinicmeded.com\/live\/courses\/immunodeficiency\/faculty.asp\u003c\/a\u003e\r\n\r\n\u003cstrong\u003eOfficial Accreditation Information:\u003c\/strong\u003e\r\n\r\n\u003ca href=\"https:\/\/clevelandclinicmeded.com\/live\/courses\/immunodeficiency\/geninfo.asp\" data-rich-text-autolink=\"\"\u003ehttps:\/\/clevelandclinicmeded.com\/live\/courses\/immunodeficiency\/geninfo.asp\u003c\/a\u003e\r\n\r\nThese references describe the original educational program, faculty, accreditation, and scheduled presentations. They do not establish the exact inventory of files available through a separately distributed MedicalAmboss listing.\r\n\r\n\u003cstrong\u003eMedicalAmboss File Scope:\u003c\/strong\u003e This listing describes the educational subject matter for reference. Provider registration, live attendance, streaming-platform access, CME or other credit, certificates, memberships, apps, accounts, and publisher-hosted extras are not included unless explicitly listed as store files.\r\n\u003cdiv\u003e\r\n\r\n\u003chr\u003e\r\n\r\n\u003c\/div\u003e\r\n\u003ch2\u003eShort Description\u003c\/h2\u003e\r\n\u0026lt;div style=\"border:2px solid #1677b8;border-radius:10px;padding:16px;background:#f7fbfe;\"\u0026gt;\r\n\r\n\u003cstrong\u003eCleveland Clinic Updates in Primary Immunodeficiency 2026\u003c\/strong\u003e provides a comprehensive, evidence-based review of inborn errors of immunity, including common variable immunodeficiency (CVID), antibody deficiencies, cellular immune disorders, hematologic complications, recurrent infections, and emerging treatment strategies.\r\n\r\nThe September 18–19, 2026 symposium features expert-led educational sessions covering immune dysregulation, diagnostic vaccination guidelines, chronic neutropenia, immune thrombocytopenia, cancer risk, artificial intelligence, biologic therapy, immunoglobulin replacement, antimicrobial prophylaxis, and stem cell transplantation.\r\n\r\n\u003cstrong\u003e Topics:\u003c\/strong\u003e\r\n\u003ctable id=\"day1-table\" class=\"agenda agendaBorderColor\" border=\"0\" width=\"100%\" cellspacing=\"0\" cellpadding=\"0\"\u003e\r\n\u003ctbody\u003e\r\n\u003ctr class=\"header\"\u003e\r\n\u003ctd class=\"agendaBorderColor agendaRowShade borderBottom1px\" colspan=\"2\" height=\"auto\"\u003e\r\n\u003ch3 class=\"white\"\u003eFriday, September 18, 2026\r\n\u003cem class=\"agenda-alltimes\"\u003eAll times in Eastern Time\u003c\/em\u003e\n\u003c\/h3\u003e\r\n\u003c\/td\u003e\r\n\u003c\/tr\u003e\r\n\u003ctr\u003e\r\n\u003ctd width=\"15%\"\u003e\r\n\u003cdiv align=\"right\"\u003e7:15 am\u003c\/div\u003e\n\u003c\/td\u003e\r\n\u003ctd valign=\"top\"\u003e\u003cstrong\u003eRegistration, Breakfast and Visit Exhibits\u003c\/strong\u003e\u003c\/td\u003e\r\n\u003c\/tr\u003e\r\n\u003ctr\u003e\r\n\u003ctd width=\"15%\"\u003e\r\n\u003cdiv align=\"right\"\u003e7:50 am\u003c\/div\u003e\n\u003c\/td\u003e\r\n\u003ctd valign=\"top\"\u003e\n\u003cstrong\u003eWelcome \u0026amp; Introductions\u003c\/strong\u003e\r\n\u003cem\u003eJames Fernandez, MD, PhD\u003c\/em\u003e\n\u003c\/td\u003e\r\n\u003c\/tr\u003e\r\n\u003ctr\u003e\r\n\u003ctd width=\"15%\"\u003e\u003c\/td\u003e\r\n\u003ctd valign=\"top\"\u003e\r\n\u003ch4\u003e\n\u003cstrong\u003eSession 1 – Humoral Deficiency\u003c\/strong\u003e\r\n\u003cem\u003eModerator – James Fernandez, MD, PhD\u003c\/em\u003e\n\u003c\/h4\u003e\r\n\u003c\/td\u003e\r\n\u003c\/tr\u003e\r\n\u003ctr\u003e\r\n\u003ctd width=\"15%\"\u003e\r\n\u003cdiv align=\"right\"\u003e8:00 am\u003c\/div\u003e\n\u003c\/td\u003e\r\n\u003ctd valign=\"top\"\u003e\n\u003cstrong\u003eCVID – the latest\u003c\/strong\u003e\r\n\u003cem\u003eCharlotte Cunningham-Rundles, MD, PhD\u003c\/em\u003e\n\u003c\/td\u003e\r\n\u003c\/tr\u003e\r\n\u003ctr\u003e\r\n\u003ctd width=\"15%\"\u003e\r\n\u003cdiv align=\"right\"\u003e8:30 am\u003c\/div\u003e\n\u003c\/td\u003e\r\n\u003ctd valign=\"top\"\u003e\n\u003cstrong\u003eCVID like syndromes – APDS and beyond\u003c\/strong\u003e\r\n\u003cem\u003eJocelyn Farmer, MD, PhD\u003c\/em\u003e\n\u003c\/td\u003e\r\n\u003c\/tr\u003e\r\n\u003ctr\u003e\r\n\u003ctd width=\"15%\"\u003e\r\n\u003cdiv align=\"right\"\u003e9:00 am\u003c\/div\u003e\n\u003c\/td\u003e\r\n\u003ctd valign=\"top\"\u003e\n\u003cstrong\u003eUpdates in Specific Antibody Deficiency and Diagnostic Vaccination Guidelines\u003c\/strong\u003e\r\n\u003cem\u003eKelli Williams, MD, MPH\u003c\/em\u003e\n\u003c\/td\u003e\r\n\u003c\/tr\u003e\r\n\u003ctr\u003e\r\n\u003ctd width=\"15%\"\u003e\r\n\u003cdiv align=\"right\"\u003e9:30 am\u003c\/div\u003e\n\u003c\/td\u003e\r\n\u003ctd valign=\"top\"\u003e\n\u003cstrong\u003eIgE levels – what does it tell us?\u003c\/strong\u003e\r\n\u003cem\u003eMonica Lawrence, MD\u003c\/em\u003e\n\u003c\/td\u003e\r\n\u003c\/tr\u003e\r\n\u003ctr\u003e\r\n\u003ctd width=\"15%\"\u003e\r\n\u003cdiv align=\"right\"\u003e10:00 am\u003c\/div\u003e\n\u003c\/td\u003e\r\n\u003ctd valign=\"top\"\u003e\n\u003cstrong\u003ePanel Discussion\u003c\/strong\u003e\r\n\u003cem\u003eCourse Faculty\u003c\/em\u003e\n\u003c\/td\u003e\r\n\u003c\/tr\u003e\r\n\u003ctr\u003e\r\n\u003ctd width=\"15%\"\u003e\r\n\u003cdiv align=\"right\"\u003e10:20 am\u003c\/div\u003e\n\u003c\/td\u003e\r\n\u003ctd valign=\"top\"\u003e\u003cstrong\u003eRefreshment Break \u0026amp; Visit Exhibits\u003c\/strong\u003e\u003c\/td\u003e\r\n\u003c\/tr\u003e\r\n\u003ctr\u003e\r\n\u003ctd width=\"15%\"\u003e\u003c\/td\u003e\r\n\u003ctd valign=\"top\"\u003e\r\n\u003ch4\u003e\n\u003cstrong\u003eSession 2 – Hematologic Complications\u003c\/strong\u003e\r\n\u003cem\u003eModerator – James Fernandez, MD, PhD\u003c\/em\u003e\n\u003c\/h4\u003e\r\n\u003c\/td\u003e\r\n\u003c\/tr\u003e\r\n\u003ctr\u003e\r\n\u003ctd width=\"15%\"\u003e\r\n\u003cdiv align=\"right\"\u003e10:40 am\u003c\/div\u003e\n\u003c\/td\u003e\r\n\u003ctd valign=\"top\"\u003e\n\u003cstrong\u003eChronic Neutropenia – how to handle\u003c\/strong\u003e\r\n\u003cem\u003eSerhan Unlu, MD\u003c\/em\u003e\n\u003c\/td\u003e\r\n\u003c\/tr\u003e\r\n\u003ctr\u003e\r\n\u003ctd width=\"15%\"\u003e\r\n\u003cdiv align=\"right\"\u003e11:10 am\u003c\/div\u003e\n\u003c\/td\u003e\r\n\u003ctd valign=\"top\"\u003e\n\u003cstrong\u003eITP in immune disease\u003c\/strong\u003e\r\n\u003cem\u003eAlan Lichtin, MD\u003c\/em\u003e\n\u003c\/td\u003e\r\n\u003c\/tr\u003e\r\n\u003ctr\u003e\r\n\u003ctd width=\"15%\"\u003e\r\n\u003cdiv align=\"right\"\u003e11:40 am\u003c\/div\u003e\n\u003c\/td\u003e\r\n\u003ctd valign=\"top\"\u003e\n\u003cstrong\u003eCancer in Immunodeficiency – screening recommendations\u003c\/strong\u003e\r\n\u003cem\u003eJohn McDonnell, MD, MS\u003c\/em\u003e\n\u003c\/td\u003e\r\n\u003c\/tr\u003e\r\n\u003ctr\u003e\r\n\u003ctd width=\"15%\"\u003e\r\n\u003cdiv align=\"right\"\u003e12:10 pm\u003c\/div\u003e\n\u003c\/td\u003e\r\n\u003ctd valign=\"top\"\u003e\n\u003cstrong\u003ePanel Discussion\u003c\/strong\u003e\r\n\u003cem\u003eCourse Faculty\u003c\/em\u003e\n\u003c\/td\u003e\r\n\u003c\/tr\u003e\r\n\u003ctr\u003e\r\n\u003ctd width=\"15%\"\u003e\r\n\u003cdiv align=\"right\"\u003e12:30 pm\u003c\/div\u003e\n\u003c\/td\u003e\r\n\u003ctd valign=\"top\"\u003e\u003cstrong\u003eLunch, Visit Exhibits, and Optional Non-CME Satellite\u003c\/strong\u003e\u003c\/td\u003e\r\n\u003c\/tr\u003e\r\n\u003ctr\u003e\r\n\u003ctd width=\"15%\"\u003e\u003c\/td\u003e\r\n\u003ctd valign=\"top\"\u003e\r\n\u003ch4\u003e\n\u003cstrong\u003eSession 3 – Cellular Defects\u003c\/strong\u003e\r\n\u003cem\u003eModerator – James Fernandez, MD, PhD\u003c\/em\u003e\n\u003c\/h4\u003e\r\n\u003c\/td\u003e\r\n\u003c\/tr\u003e\r\n\u003ctr\u003e\r\n\u003ctd width=\"15%\"\u003e\r\n\u003cdiv align=\"right\"\u003e1:30 pm\u003c\/div\u003e\n\u003c\/td\u003e\r\n\u003ctd valign=\"top\"\u003e\n\u003cstrong\u003eIdiopathic CD4 Lymphocytopenia\u003c\/strong\u003e\r\n\u003cem\u003eJonathan Bernstein, MD\u003c\/em\u003e\n\u003c\/td\u003e\r\n\u003c\/tr\u003e\r\n\u003ctr\u003e\r\n\u003ctd width=\"15%\"\u003e\r\n\u003cdiv align=\"right\"\u003e2:00 pm\u003c\/div\u003e\n\u003c\/td\u003e\r\n\u003ctd valign=\"top\"\u003e\n\u003cstrong\u003eJob’s Syndrome and CMCC – a dermatologist’s view\u003c\/strong\u003e\r\n\u003cem\u003eAnthony Fernandez, MD, PhD\u003c\/em\u003e\n\u003c\/td\u003e\r\n\u003c\/tr\u003e\r\n\u003ctr\u003e\r\n\u003ctd width=\"15%\"\u003e\r\n\u003cdiv align=\"right\"\u003e2:30 pm\u003c\/div\u003e\n\u003c\/td\u003e\r\n\u003ctd valign=\"top\"\u003e\n\u003cstrong\u003eMendelian Susceptibility to Mycobacterial Disease\u003c\/strong\u003e\r\n\u003cem\u003eVivian Hernandez-Trujillo, MD\u003c\/em\u003e\n\u003c\/td\u003e\r\n\u003c\/tr\u003e\r\n\u003ctr\u003e\r\n\u003ctd width=\"15%\"\u003e\r\n\u003cdiv align=\"right\"\u003e3:00 pm\u003c\/div\u003e\n\u003c\/td\u003e\r\n\u003ctd valign=\"top\"\u003e\n\u003cstrong\u003eChronic Granulomatous Disease in adults (including X-linked)\u003c\/strong\u003e\r\n\u003cem\u003eAntoine Azar, MD\u003c\/em\u003e\n\u003c\/td\u003e\r\n\u003c\/tr\u003e\r\n\u003ctr\u003e\r\n\u003ctd width=\"15%\"\u003e\r\n\u003cdiv align=\"right\"\u003e3:20 pm\u003c\/div\u003e\n\u003c\/td\u003e\r\n\u003ctd valign=\"top\"\u003e\n\u003cstrong\u003ePanel Discussion\u003c\/strong\u003e\r\n\u003cem\u003eCourse Faculty\u003c\/em\u003e\n\u003c\/td\u003e\r\n\u003c\/tr\u003e\r\n\u003ctr\u003e\r\n\u003ctd width=\"15%\"\u003e\r\n\u003cdiv align=\"right\"\u003e3:40 pm\u003c\/div\u003e\n\u003c\/td\u003e\r\n\u003ctd valign=\"top\"\u003e\u003cstrong\u003eRefreshment Break and Visit Exhibits\u003c\/strong\u003e\u003c\/td\u003e\r\n\u003c\/tr\u003e\r\n\u003ctr\u003e\r\n\u003ctd width=\"15%\"\u003e\u003c\/td\u003e\r\n\u003ctd valign=\"top\"\u003e\r\n\u003ch4\u003e\n\u003cstrong\u003eSession 4 – Complex Disease and Future Options\u003c\/strong\u003e\r\n\u003cem\u003eModerator – James Fernandez, MD, PhD\u003c\/em\u003e\n\u003c\/h4\u003e\r\n\u003c\/td\u003e\r\n\u003c\/tr\u003e\r\n\u003ctr\u003e\r\n\u003ctd width=\"15%\"\u003e\r\n\u003cdiv align=\"right\"\u003e4:00 pm\u003c\/div\u003e\n\u003c\/td\u003e\r\n\u003ctd valign=\"top\"\u003e\n\u003cstrong\u003eThinking outside the box: diagnostic immunology evaluation of the complex immunology patient\u003c\/strong\u003e\r\n\u003cem\u003eRoshini Abraham, PhD, D(ABMLI)\u003c\/em\u003e\n\u003c\/td\u003e\r\n\u003c\/tr\u003e\r\n\u003ctr\u003e\r\n\u003ctd width=\"15%\"\u003e\r\n\u003cdiv align=\"right\"\u003e4:30 pm\u003c\/div\u003e\n\u003c\/td\u003e\r\n\u003ctd valign=\"top\"\u003e\n\u003cstrong\u003eUsing Artificial Intelligence to your advantage in practice\u003c\/strong\u003e\r\n\u003cem\u003eNicholas Rider, DO\u003c\/em\u003e\n\u003c\/td\u003e\r\n\u003c\/tr\u003e\r\n\u003ctr\u003e\r\n\u003ctd width=\"15%\"\u003e\r\n\u003cdiv align=\"right\"\u003e5:00 pm\u003c\/div\u003e\n\u003c\/td\u003e\r\n\u003ctd valign=\"top\"\u003e\n\u003cstrong\u003eBiologics use in the immunocompromised\u003c\/strong\u003e\r\n\u003cem\u003eJolan Walter, MD, PhD\u003c\/em\u003e\n\u003c\/td\u003e\r\n\u003c\/tr\u003e\r\n\u003ctr\u003e\r\n\u003ctd width=\"15%\"\u003e\r\n\u003cdiv align=\"right\"\u003e5:30 pm\u003c\/div\u003e\n\u003c\/td\u003e\r\n\u003ctd valign=\"top\"\u003e\n\u003cstrong\u003ePanel Discussion\u003c\/strong\u003e\r\n\u003cem\u003eCourse Faculty\u003c\/em\u003e\n\u003c\/td\u003e\r\n\u003c\/tr\u003e\r\n\u003ctr\u003e\r\n\u003ctd width=\"15%\"\u003e\r\n\u003cdiv align=\"right\"\u003e5:45 pm\u003c\/div\u003e\n\u003c\/td\u003e\r\n\u003ctd valign=\"top\"\u003e\u003cstrong\u003eAdjourn\r\nReception and Optional Non-CME Satellite\u003c\/strong\u003e\u003c\/td\u003e\r\n\u003c\/tr\u003e\r\n\u003c\/tbody\u003e\r\n\u003c\/table\u003e\r\n \r\n\u003ctable id=\"day2-table\" class=\"agenda agendaBorderColor\" border=\"0\" width=\"100%\" cellspacing=\"0\" cellpadding=\"0\"\u003e\r\n\u003ctbody\u003e\r\n\u003ctr class=\"header\"\u003e\r\n\u003ctd class=\"agendaBorderColor agendaRowShade borderBottom1px\" colspan=\"2\" height=\"auto\"\u003e\n\u003ca id=\"day2\" name=\"day2\"\u003e\u003c\/a\u003e\r\n\u003ch3 class=\"white\"\u003eSaturday, September 19, 2026\r\n\u003cem class=\"agenda-alltimes\"\u003eAll times in Eastern Time\u003c\/em\u003e\n\u003c\/h3\u003e\r\n\u003c\/td\u003e\r\n\u003c\/tr\u003e\r\n\u003ctr\u003e\r\n\u003ctd width=\"15%\"\u003e\r\n\u003cdiv align=\"right\"\u003e7:15 am\u003c\/div\u003e\n\u003c\/td\u003e\r\n\u003ctd valign=\"top\"\u003e\u003cstrong\u003eRegistration, Breakfast, Visit Exhibits and Optional Non-CME Satellite\u003c\/strong\u003e\u003c\/td\u003e\r\n\u003c\/tr\u003e\r\n\u003ctr\u003e\r\n\u003ctd width=\"15%\"\u003e\r\n\u003cdiv align=\"right\"\u003e7:55 am\u003c\/div\u003e\n\u003c\/td\u003e\r\n\u003ctd valign=\"top\"\u003e\n\u003cstrong\u003eWelcome \u0026amp; Introductions\u003c\/strong\u003e\r\n\u003cem\u003eJames Fernandez, MD, PhD\u003c\/em\u003e\n\u003c\/td\u003e\r\n\u003c\/tr\u003e\r\n\u003ctr\u003e\r\n\u003ctd width=\"15%\"\u003e\u003c\/td\u003e\r\n\u003ctd valign=\"top\"\u003e\r\n\u003ch4\u003e\n\u003cstrong\u003eSession 5 – Therapies for IEI \u0026amp; Cases with the Experts\u003c\/strong\u003e\r\n\u003cem\u003eModerator – James Fernandez, MD, PhD\u003c\/em\u003e\n\u003c\/h4\u003e\r\n\u003c\/td\u003e\r\n\u003c\/tr\u003e\r\n\u003ctr\u003e\r\n\u003ctd width=\"15%\"\u003e\r\n\u003cdiv align=\"right\"\u003e8:00 am\u003c\/div\u003e\n\u003c\/td\u003e\r\n\u003ctd valign=\"top\"\u003e\n\u003cstrong\u003eThe Headaches of Immunoglobulin Replacement- literally and figuratively\u003c\/strong\u003e\r\n\u003cem\u003eJames Fernandez, MD, PhD\u003c\/em\u003e\n\u003c\/td\u003e\r\n\u003c\/tr\u003e\r\n\u003ctr\u003e\r\n\u003ctd width=\"15%\"\u003e\r\n\u003cdiv align=\"right\"\u003e8:30 am\u003c\/div\u003e\n\u003c\/td\u003e\r\n\u003ctd valign=\"top\"\u003e\n\u003cstrong\u003eAntibiotic resistance and prophylaxis\u003c\/strong\u003e\r\n\u003cem\u003eCarlos Isada, MD\u003c\/em\u003e\n\u003c\/td\u003e\r\n\u003c\/tr\u003e\r\n\u003ctr\u003e\r\n\u003ctd width=\"15%\"\u003e\r\n\u003cdiv align=\"right\"\u003e9:00 am\u003c\/div\u003e\n\u003c\/td\u003e\r\n\u003ctd valign=\"top\"\u003e\n\u003cstrong\u003eHSCT for adults with immunodeficiencies\u003c\/strong\u003e\r\n\u003cem\u003eLarisa Broglie, MD, MS\u003c\/em\u003e\n\u003c\/td\u003e\r\n\u003c\/tr\u003e\r\n\u003ctr\u003e\r\n\u003ctd width=\"15%\"\u003e\r\n\u003cdiv align=\"right\"\u003e9:30 am\u003c\/div\u003e\n\u003c\/td\u003e\r\n\u003ctd valign=\"top\"\u003e\n\u003cstrong\u003eDifficult Cases with the Experts – case 1\u003c\/strong\u003e\r\n\u003cem\u003ePresenter – John McDonnell, MD, MS\r\nModerator – James Fernandez, MD, PhD\u003c\/em\u003e\n\u003c\/td\u003e\r\n\u003c\/tr\u003e\r\n\u003ctr\u003e\r\n\u003ctd width=\"15%\"\u003e\r\n\u003cdiv align=\"right\"\u003e10:00 am\u003c\/div\u003e\n\u003c\/td\u003e\r\n\u003ctd valign=\"top\"\u003e\n\u003cstrong\u003eDifficult Cases with the Experts – case 2\u003c\/strong\u003e\r\n\u003cem\u003ePanel – Charlotte Cunningham-Rundles, MD, PhD, John McDonnell, MD, MS, and Jolan Walter, MD, PhD\u003c\/em\u003e\n\u003c\/td\u003e\r\n\u003c\/tr\u003e\r\n\u003ctr\u003e\r\n\u003ctd width=\"15%\"\u003e\r\n\u003cdiv align=\"right\"\u003e10:20 am\u003c\/div\u003e\n\u003c\/td\u003e\r\n\u003ctd valign=\"top\"\u003e\u003cstrong\u003eRefreshment Break \u0026amp; Visit Exhibits\u003c\/strong\u003e\u003c\/td\u003e\r\n\u003c\/tr\u003e\r\n\u003ctr\u003e\r\n\u003ctd width=\"15%\"\u003e\u003c\/td\u003e\r\n\u003ctd valign=\"top\"\u003e\r\n\u003ch4\u003e\n\u003cstrong\u003eSession 6 – Common Symptoms in the Immunocompromised\u003c\/strong\u003e\r\n\u003cem\u003eModerator – James Fernandez, MD, PhD\u003c\/em\u003e\n\u003c\/h4\u003e\r\n\u003c\/td\u003e\r\n\u003c\/tr\u003e\r\n\u003ctr\u003e\r\n\u003ctd width=\"15%\"\u003e\r\n\u003cdiv align=\"right\"\u003e10:40 am\u003c\/div\u003e\n\u003c\/td\u003e\r\n\u003ctd valign=\"top\"\u003e\n\u003cstrong\u003eDifficult Cases with the Experts – case 3\u003c\/strong\u003e\r\n\u003cem\u003eDylan Timberlake, MD\u003c\/em\u003e\n\u003c\/td\u003e\r\n\u003c\/tr\u003e\r\n\u003ctr\u003e\r\n\u003ctd width=\"15%\"\u003e\r\n\u003cdiv align=\"right\"\u003e11:10 am\u003c\/div\u003e\n\u003c\/td\u003e\r\n\u003ctd valign=\"top\"\u003e\n\u003cstrong\u003eMusculoskeletal pain in AB def patients – diagnostic and therapeutic difficulties\u003c\/strong\u003e\r\n\u003cem\u003eCassandra Calabrese, DO\u003c\/em\u003e\n\u003c\/td\u003e\r\n\u003c\/tr\u003e\r\n\u003ctr\u003e\r\n\u003ctd width=\"15%\"\u003e\r\n\u003cdiv align=\"right\"\u003e11:40 am\u003c\/div\u003e\n\u003c\/td\u003e\r\n\u003ctd valign=\"top\"\u003e\n\u003cstrong\u003eChronic Sinusitis – when to be concerned\u003c\/strong\u003e\r\n\u003cem\u003eTroy Woodard, MD\u003c\/em\u003e\n\u003c\/td\u003e\r\n\u003c\/tr\u003e\r\n\u003ctr\u003e\r\n\u003ctd width=\"15%\"\u003e\r\n\u003cdiv align=\"right\"\u003e12:10 pm\u003c\/div\u003e\n\u003c\/td\u003e\r\n\u003ctd valign=\"top\"\u003e\n\u003cstrong\u003ePanel Discussion\u003c\/strong\u003e\r\n\u003cem\u003eCourse Faculty\u003c\/em\u003e\n\u003c\/td\u003e\r\n\u003c\/tr\u003e\r\n\u003ctr\u003e\r\n\u003ctd width=\"15%\"\u003e\r\n\u003cdiv align=\"right\"\u003e12:30 pm\u003c\/div\u003e\n\u003c\/td\u003e\r\n\u003ctd valign=\"top\"\u003e\n\u003cstrong\u003eClosing Remarks\u003c\/strong\u003e\r\n\u003cem\u003eJames Fernandez, MD, PhD\u003c\/em\u003e\n\u003c\/td\u003e\r\n\u003c\/tr\u003e\r\n\u003ctr\u003e\r\n\u003ctd width=\"15%\"\u003e\r\n\u003cdiv align=\"right\"\u003e12:35 pm\u003c\/div\u003e\n\u003c\/td\u003e\r\n\u003ctd valign=\"top\"\u003e\u003cstrong\u003eAdjourn\u003c\/strong\u003e\u003c\/td\u003e\r\n\u003c\/tr\u003e\r\n\u003c\/tbody\u003e\r\n\u003c\/table\u003e\r\n\u003c\/div\u003e\r\n\u003csection class=\"medicalamboss-related-resources\"\u003e\u003c\/section\u003e","brand":"Amboss","offers":[{"title":"Default Title","offer_id":67967781273754,"sku":"MED-AMB10536","price":60.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0720\/8619\/2282\/files\/macs-0efe51bcb5-50427-50435-710ec0e407251a661c64.jpg?v=1793059374","url":"https:\/\/ambosscourse.com\/products\/wc-0efe51bcb5f34c14-50427","provider":"Amboss","version":"1.0","type":"link"}